Call for Abstract
3rd International Conference on Enzymology and Molecular Biology, will be organized around the theme “Disentangling diversity in complex enzymes”
Enzymology 2018 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Enzymology 2018
Submit your abstract to any of the mentioned tracks.
Register now for the conference by choosing an appropriate package suitable to you.
Biochemistry, sometimes called biological chemistry, is the study of chemical processes within and relating to living organisms. By controlling information flow through biochemical signalling and the flow of chemical energy through metabolism, biochemical processes give rise to the complexity of life. Over the last decades of the 20th century, biochemistry has become so successful at explaining living processes that now almost all areas of the life sciences from botany to medicine to genetics are engaged in biochemical research. Today, the main focus of pure biochemistry is on understanding how biological molecules give rise to the processes that occur within living cells, which in turn relates greatly to the study and understanding of tissues, organs, and whole organisms - that is, all of biology.
- Track 1-1Biochemical processes
- Track 1-2Enzymatic chemistry
- Track 1-3Biochemical signaling
- Track 1-4Membrane biochemistry
- Track 1-5Activation of enzyme
- Track 1-6Neurodevelopmental Disorders
Molecular enzymology is designing and synthesis of enzymes and high unmet medical needs are based on innovative drug targets. The work of designing and synthesis of enzymes and high unmet medical need are based on innovative drug targets.
Molecular Enzymology's interest include in all aspects related to enzymes like discovery of enzymes, enzyme structure, enzyme mechanisms, cellular and metabolic functions of enzymes, exploitation of enzymes for biotechnological and pharmaceutical applications, drug discovery, biochemical aspects of enzymes, bioinformatics, computational analysis, molecular modelling studies, new methods in enzyme expression and purification, bio catalysis, bio molecular engineering, enzyme kinetics and inhibitors.
- Track 2-1Designing of enzymes
- Track 2-2Synthesis of enzymes
- Track 2-3Enzyme mechanisms
- Track 2-4Bio molecular engineering
- Track 2-5Enzyme expression
Enzymes are proteins processing cellular metabolism. They can affect a reaction by catalysing and they can be used to reverse the reaction in bio-chemical pathways. Though enzymes have complex enzyme structure they undergo many changes which is very important for reactions and so enzyme structure is very important. There is a specific enzyme for specific reaction.
Enzymes structures are made up of α amino acids which are linked together via amide (peptide) bonds in a linear chain. This is the primary structure. The resulting amino acid chain is called a polypeptide or protein. The specific order of amino acids in the protein is encoded by the DNA sequence of the corresponding gene.
- Track 3-1Bio-chemical pathways of enzymes
- Track 3-2 Metabolic pathway of enzymes
- Track 3-3Activation energy of enzymes
- Track 3-4"Lock and key" model of Enzymes
- Track 3-5Exploitation of enzymes
Enzymes are the extremely selective biocatalysts synthesized by living cells. Therapeutic enzymes are those enzymes which can be used medically either isolately or adjunctly with other therapies with the purpose of treatment of various diseases safely. Use of these enzymes as drugs for the treatment of medical problems forms the basis for “Therapeutic use of enzymes”. Enzyme supplements are often prescribed for patience suffering from disorders that affect the digestive processes such as Cysic fibrosis, Gaucher'"s disease and celiac disease. Enzymes have the ability to purify the blood,stenghen the immune system, enhance the mental capacity, cleanse the colon and maintain the proper pH balance in urine. Enzyme immobilization is another broad field which is applied in therapeutics. Immobilization process is to optimize the operational perforformance of an enzyme for industrial application. Immobilization improves many properties of enzymes such as performance in organic solvents, pH tolerance, selectivity, heat stability and functional stability.
- Track 4-1Enzyme therapy in cancer
- Track 4-2Therapeutic enzymes in drug delivery
- Track 4-3Clinical application of immobilized enzymes
- Track 4-4Whole cell immobilization
- Track 4-5Immobilized enzymes in antibiotic production
- Track 4-6Metallozymes
Cell signalling is part of any communication process that governs basic activities of cell and coordinates all cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in signalling interactions and cellular information processing are responsible for diseases such as cancer autoimmunity and diabetes.Cells have proteins called receptors that bind to signalling molecule and initiate a physiological response. Receptors transform external signals into internal ones via protein action, ion channel opening or enzyme activation.
- Track 5-1Signal transduction mechanism
- Track 5-2Receptor activity
- Track 5-3Signal pathways
- Track 5-4Kinase targets
- Track 5-5G-protein
The nanomaterials possess ideal characteristics to equilibrate principal factors which determine biocatalysts efficiency, including specific surface area, mass transfer resistance and effective enzyme loading. This review presents the current scenario and techniques in enzyme immobilization. Some methods are used which are efficient to combine proteins/enzymes with nanoparticles. Immobilization process is to optimize the operational performance of an enzyme for industrial applications. So far different matrices have been described in the literature to improve the performance of the immobilized enzymes. With the advent of nanotechnology, the nanomaterials because of their unique physico-chemical properties constitute novel and interesting matrices for enzyme immobilization.
- Track 6-1Enzyme nanoparticles
- Track 6-2DNA nanotechnology
- Track 6-3Nanotechnology products
- Track 6-4DNA microarray
- Track 6-5Nanopolymers
- Track 6-6Nanotechnology in targeted drug delivery
- Track 6-7Immobilization using nanoparticles
- Track 6-8Nanotechnology enabled enzyme activity
Enzymes are catalysts that increase the rate or velocity of physiologic reactions. Each and every reaction in our body takes place with the help of an enzyme. In general, most enzymes are present in cells at much higher concentrations than in plasma. Measurement of their levels in plasma indicates whether their tissue of origin is damaged leading to the release of intracellular components into the blood. This forms the basis of clinical enzymology. Thus clinical enzymology refers to measurement of enzyme activity for the diagnosis and treatment of diseases.
- Track 7-1Spectrometry, electrophoresis & immunoassay
- Track 7-2Chemical pathology
- Track 7-3Toxicology
Enzyme kinetics is the study of the chemical reactions that are catalysed by enzymes. In enzyme kinetics, the reaction rate is measured and the effects of varying the conditions of the reaction are investigated. Studying an enzyme's kinetics in this way can reveal the catalytic mechanism of this enzyme, its role in metabolism, how its activity is controlled, and how a drug or an agonist might inhibit the enzyme.
- Track 8-1Immunoassays for protein detection
- Track 8-2Catalytic mechanisms of enzymes
- Track 8-3Chemical reactions of enzymes
- Track 8-4Activation of enzymes
- Track 8-5Inhibition of enzymes
Recombinant DNA technology involves joining together of DNA molecules to produce some new genetic combinations by inserting it into a host organism. Now a days Scientists are carrying out many novel researches in the field of recombinant DNA technology to bring revolution in the field of genetic engineering of crops, animals and medicine.
- Track 9-1DNA cloning
- Track 9-2Recombinant DNA applications
- Track 9-3Enzymes in recombinant DNA technology
- Track 9-4Transgenic crops and animals
Enzymes are the proteins in the drug design that act as drug targets for the diseases in the process of drug discovery and development. There are number of drug targets involved in the designing of the drug.
Drug target as a nucleic acid or a protein (e.g. an enzyme, a receptor) whose activity can be modified by a drug. The drug can be a small-molecular-weight chemical compound or a biological, such as an antibody or a recombinant protein. The drug target should have been shown to be effective/mechanistically involved in the disease by relevant in vitro or in vivo models.
- Track 10-1Drug designing using enzymes
- Track 10-2Drug development using enzymes
- Track 10-3Drug modelling
- Track 10-4 Drug targeting
Proteomics is the large-scale study of proteins, particularly their structures and functions. Proteins are vital parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. The term proteomics was first coined in 1997 to make an analogy with genomics, the study of the genome. The word proteome is a portmanteau of protein and genome. The proteome is the entire set of proteins, produced or modified by an organism or system.
- Track 11-1Post-translational modifications of proteins
- Track 11-2Methods of studying proteins
- Track 11-3Biomarkers
- Track 11-4Hybrid technologies
- Track 11-5Hybrid technologies
- Track 11-6Mass spectroscopy & protein profiling
Chemical, physical and structural aspects of each molecule add to their funtional activity in the cell. These chemical interactions, binding activity, binding energy, other physical variables which contribute to the biophysics of a biomolecule.Structural biology deals with strategical engagement of each molecule with another interms of their binding and structural integrity. Chemical reactions associated with each them acts as basis for the biochemistry of that molecule.Especially biochemistry of protein which is involved in day today metabolism of human body.
- Track 15-1Cellular and Molecular Genetics
- Track 15-2Genomics: Disease and Evolution
- Track 15-3Stem cells and Regenerative Medicine
- Track 15-4Bioinformatics in Human Genetics
- Track 15-5Cytogenetics
- Track 15-6Cancer and Genome Integrity
- Track 15-7Congenital Disorders
- Track 15-8Transplanation
Molecular simulations and modelling are changing the science of enzymology. Calculations can provide detailed, atomic-level insight into the fundamental mechanisms of biological catalysts. Computational enzymology is a rapidly developing area, and is testing theories of catalysis, challenging 'textbook' mechanisms, and identifying novel catalytic mechanisms. Increasingly, modelling is contributing directly to experimental studies of enzyme-catalysed reactions. Potential practical applications include interpretation of experimental data, catalyst design and drug development.
- Track 16-1Molecular simulations of enzymes
- Track 16-2Molecular modelling of enzymes
- Track 16-3Fundamental mechanisms of biological catalysts
In the presence of an enzyme, the reaction runs in the same direction as it would without the enzyme, just more quickly. For example, carbonic anhydrase catalyses its reaction in either direction depending on the concentration of its reactants. The rate of a reaction is dependent on the activation energy needed to form the transition state which then decays into products. Enzymes increase reaction rates by lowering the energy of the transition state. First, binding forms a low energy enzyme-substrate complex (ES). Secondly the enzyme stabilises the transition state such that it requires less energy to achieve compared to the uncatalyzed reaction (ES‡). Finally the enzyme-product complex (EP) dissociates to release the products.
- Track 17-1Catalytic mechanisms of enzymes
- Track 17-2Applications of immobilized enzymes in food
- Track 17-3Enzymes in food digestion
- Track 17-4Product recovery
- Track 17-5 Production of biomass
- Track 17-6Production of extracellular metabolites
- Track 17-7Production of intracellular components
- Track 17-8Transformation of substrate
- Track 17-9Transition state of enzymes
- Track 17-10Enzyme-substrate complex
- Track 17-11Single cell protein
Food enzymology includes the all the aspects of the enzymology important to the food systems. The basic aspects of the food enzymology include: methods of measuring enzymatic activities; extraction of enzymes from microbial,plant and animal systems; methods of enzyme purification and characterization; and regulation of enzyme activities by activators, inhibitors, and by covalent modification. Applied aspects of the course focus on enzymes used by the food industry and methods for controlling endogenous enzyme activities.
A case study is generally a documented study of a specific real-life situation or imagined scenario, used as a training tool in business schools and firms. Students or trainees are required to analyse the prescribed cases and present their interpretations or solutions, supported by the line of reasoning employed and assumptions made. The case study consists of various notes that represent the particular patient. The detail of the particular patient such as laboratory findings, Medical history, Family history, Social history, Physical examination, Treatment plan etc.